Microfluidics and Organ-on-Chip Technologies: Reimagining Innovation, Health, and Wellbeing for a Sustainable Future
My keynote will explore how Organ-on-Chip (OOC) and Lab-on-Chip (LOC) technologies—miniaturized platforms that replicate the physiological functions of human organs—are transforming the landscape of healthcare, sustainability, and ethical innovation. These emerging systems enable precise disease modelling, humane and data-driven drug testing, and personalized treatment approaches. Their development reflects a broader global movement toward scientific progress grounded in responsibility and mindfulness, aligning closely with Bhutan’s developmental vision under the framework of Gross National Happiness (GNH).
Drawing upon my research at the University of Sydney, I will discuss how our team has pioneered a new generation of microfluidic platforms capable of biomimetic organ modelling, including liver, lung, and cancer tissues for accurate drug evaluation and toxicity studies. We have also advanced animal-on-a-chip systems that provide humane and high-fidelity alternatives to traditional animal testing, and multi-organ integration or “human-on-a-chip” technologies that simulate body-wide interactions to improve predictive healthcare. Complemented by ongoing research in AI-driven microfluidic optimization, these innovations promise scalable, personalized, and accessible healthcare solutions for both human and veterinary medicine.
Beyond biotechnology, this keynote connects frontier science to Bhutan’s holistic philosophy of wellbeing and mindful innovation. It argues that technology must evolve in balance with compassion and sustainability, creating pathways for Bhutan and the broader global community to lead in ethical, human-centred scientific ecosystems. This vision resonates strongly with the ABRC 2025 themes of Innovation in Higher Education, Digital Mindfulness and Human–Technology Relations, and Integration of STEM for Societal Impact, positioning scientific advancement as a bridge between innovation, ethics, and the collective pursuit of happiness.
